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Calcitriol Regulates Genes That Make Proteins

Posted by Blog Thursday, March 3, 2011

Calcitriol Regulates Genes That Make Proteins


Inside the nucleus of the cell, calcitriol assists in the transfer of genetic code information. One example of this is when calcitriol binds to a transcription factor that regulates the production of calcium transport proteins. These transport proteins assist calcium absorption in the intestines.

 Dozens of genes in cells throughout the body are regulated with calcitriol. Calcitriol works with the retinoic acid form of vitamin A and thyroid hormone to produce important proteins. Calcium and phosphorus levels in the blood are maintained by the hormone calcitriol. The kidneys release just enough calcitriol into the blood to regulate blood levels of these minerals.


Calcitriol Inhibits the Proliferation of Cells



Some tissues in the body are able to make their own calcitriol from calcidiol. The calcitriol made in tissues outside the kidneys is not used to regulate calcium and phosphorus. The calcitriol made in tissues outside of the kidneys may play an anticancer role by slowing cell division.



More about D- Vitamin:

Vitamin D

Sunlight and Vitamin D

Activation of Vitamin D

Calcitriol Regulates Genes That Make Proteins

How Vitamin D Controls Calcium

Deficiency of Vitamin D

Sources of Vitamin D


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