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COPPER AND ANTIOXIDANT ACTIVITY

Posted by Blog Tuesday, March 29, 2011

One of the most powerful antioxidants in the body is superoxide dismutase (SOD). Two forms of SOD contain copper. One is copper/zinc SOD that protects red blood cells. The other is an extracellular SOD found in high amounts in the lungs. SOD protects against the superoxide radical by converting it to hydrogen peroxide, which is then broken down to water. Copper also helps prevent iron from becoming a free radical.

Summary for Copper
Main functions: energy production, collagen synthesis, iron transport, and as an antioxidant.
RDA: adults, 900 mcg.
Toxicity: rare.
Tolerable upper intake level is 10 mg for adults.
Deficiency can cause anemia.
Sources: nuts and seeds, avocados, and green leafy vegetables such as spinach.
Forms in the body: found in cytochrome c oxidase, lysyl oxidase, and some forms of superoxide dismutase.


COPPER DEFICIENCY
Copper deficiency is rare. One of the clinical signs of copper deficiency is anemia that does not respond to iron supplementation. Copper deficiency can also lead to low numbers of white blood cells, which can increase susceptibility to infection. Premature and malnourished infants are vulnerable to copper deficiency if they are fed formula made with cow’s milk, which is low in copper. Children with cystic fibrosis may be more vulnerable to copper deficiency.


More about Copper:

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