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Iron Deficiency

Posted by Blog Sunday, March 6, 2011

The highest prevalence of iron deficiency is found in infants, children, adolescents, and women of childbearing age, especially pregnant women. Infants have very high iron requirements during the weaning period. Deficiency of iron in the diet does not immediately cause iron deficiency anemia.

Stores of iron are normally depleted slowly with no anemic effects until iron stores are very low. Even before signs of anemia occur, signs of apathy and fatigue may be apparent. Some children may be incorrectly diagnosed with attention deficit disorders when they are actually suffering from iron depletion.

After iron stores are depleted, blood cells begin to have less hemoglobin and the blood cells start to become smaller than usual. With less hemoglobin than needed, oxygen delivery to the cells becomes inadequate, especially during exertion. There are other causes of anemia, such as deficiency of vitamin B12 or folate.

Symptoms of iron deficiency anemia are usually a result of inadequate oxygen delivery. Symptoms include fatigue, rapid heart rate, reduced work capacity, and rapid breathing upon exertion. Iron deficiency can also limit the ability to maintain body temperature in cold conditions. Both hemoglobin in blood and myoglobin in muscles become depleted. Lack of iron may also limit the creation of energy in the electron transport chain.
This may lead to more anaerobic energy production resulting in excess lactic acid and fatigue. Severe iron deficiency anemia can result in spoon-shaped, brittle nails, taste bud atrophy, and mouth sores.


Symptoms of iron deficiency anemia are usually a result of inadequate oxygen delivery.

Lack of sufficient iron in early childhood can contribute to problems with learning, memory, and behavior. Supplementation may prevent further problems, but may not correct existing iron deficiency problems. Iron deficiency has been found to increase the intestinal absorption of lead, which contributes to learning and memory problems.


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